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Top neurologylive.com News

Parkinson's Discovery Suggests We Could Have an FDA-Approved Treatment Already

Parkinson's Discovery Suggests We Could Have an FDA-Approved Treatment Already

67% Center coverage: 3 sources

Researchers have discovered how a surface protein on brain cells, called Aplp1, can play a role in spreading material responsible for Parkinson's disease from cell to cell in the brain.See the Story

Symptoms Timeline and Outcomes in Amyotrophic Lateral Sclerosis Using Artificial Intelligence

Healthcare · Spain

Symptoms Timeline and Outcomes in Amyotrophic Lateral Sclerosis Using Artificial Intelligence

100% Center coverage: 1 sources

Amyotrophic lateral sclerosis (ALS) is a fatal, neurodegenerative motor neuron disease. Although an early diagnosis is crucial to provide adequate care and improve survival, patients with ALS experience a significant diagnostic delay. This study aimed to use real-world data to describe the clinical profile and timing between symptom onset, diagnosis, and relevant outcomes in ALS. Retrospective and multicenter study in 5 representative hospitals …See the Story

RemeGen's Telitacicept (RC18) Received Orphan Drug Designation From EMA for Myasthenia Gravis

RemeGen's Telitacicept (RC18) Received Orphan Drug Designation From EMA for Myasthenia Gravis

100% Center coverage: 1 sources

/PRNewswire/ -- On June 16, 2025, RemeGen Co., Ltd. ("RemeGen", stock symbols: 688331.SH/09995.HK) announced that telitacicept (RC18; brand name: 泰爱®) has...See the Story

AbbVie's Migraine Drug Outperforms Generic Treatment In Head-To-Head Trial - AbbVie (NYSE:ABBV)

100% Center coverage: 1 sources

AbbVie Inc (NYSE:ABBV) on Wednesday released topline results from its Phase 3 TEMPLE study evaluating the tolerability, safety, and efficacy of atogepant (QULIPTA/AQUIPTA, 60 mg once daily) compared to the highest tolerated dose of topiramate (50, 75 or 100 mg/day) in adult patients with a history of four or more migraine days per month. The study met the primary endpoint of treatment discontinuation due to adverse events (AEs), demonstrating th…See the Story

The Role of Gene Therapy for Patients with Duchenne Muscular Dystrophy

A panelist discusses how gene therapy using microdystrophin delivered through AAV vectors shows promise for DMD treatment, though challenges remain with delivery efficiency and determining which patients will benefit most.See the Story

The Overlooked Role of Obstructive Sleep Apnea in Alzheimer Pathogenesis

Omonigho Michael Bubu, MD, PhD, an associate professor of psychiatry, neurology, & population health at NYU Langone, discussed how OSA contributes to Alzheimer disease risk through race- and sex-specific mechanisms and neurodegenerative biomarkers.Maryland · Maryland Read Article

Post Hoc Analyses Shed Light on Safety and Efficacy of Once-Nightly Sodium Oxybate in Narcolepsy Care

Richard Bogan, MD, FCCP, FAASM, an associate clinical professor at the University of South Carolina School of Medicine, discussed a bevy of presentations from the 2025 SLEEP Annual Meeting highlighting the effects of once-nightly sodium oxybate.Maryland · Maryland Read Article

Aetna Joins UnitedHealthcare and Anthem in Authorizing PoNS Device Claims for Patients With MS

NeurologyLive is your direct connection to the latest neurology news and interviews with expert neurologists in multimedia formats.Read Article

Centessa to Advance Orexin Agonist ORX142 to Clinical Trials Following IND Acceptance

Centessa Pharmaceuticals initiates Phase 1 study for ORX142, a novel orexin receptor agonist targeting neurological disorders, promising new treatment avenues.Read Article

The Importance of Early Intervention in Duchenne Muscular Dystrophy

A panelist discusses how comprehensive care for DMD patients involves early diagnosis, steroid treatment, consideration of mutation-specific therapies like exon skipping or gene therapy, and consistent monitoring by a multidisciplinary clinical team.Read Article

Phase 2B ExTINGUISH Trial Aims to Assess Efficacy of Inebilizumab for NMDAR Encephalitis

The ExTINGUISH trial investigates inebilizumab's efficacy for NMDAR encephalitis, aiming to enhance treatment options for diverse patient populations.Read Article

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