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Phenotypic and Genotypic Detection of Carbapenem Resistance in Urinary Enterobacterales Isolates: A Prospective Cross-Sectional Diagnostic Evaluation Study
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Phenotypic and Genotypic Detection of Carbapenem Resistance in Urinary Enterobacterales Isolates: A Prospective Cross-Sectional Diagnostic Evaluation Study
This study highlights the growing prevalence of carbapenem-resistant Enterobacteriaceae (CRE) in urinary tract infections, driven mainly by carbapenemase enzymes such as NDM and OXA-48-like, particularly in Escherichia coli and Klebsiella pneumoniae. Among 350 isolates, 110 were confirmed as carbapenem-resistant by PCR, underscoring significant resistance levels. While the Carba-NP test showed high specificity, its lower sensitivity compared to …
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