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Pharma Giants Pfizer and Novo Nordisk Battle Over Obesity Drug Innovator Metsera

Pfizer accuses Novo Nordisk of anticompetitive conduct to block a $7.3 billion Metsera acquisition that could challenge GLP-1 drug market dominance, Pfizer said.

  • On Monday, Pfizer filed a second antitrust lawsuit in the U.S. District Court for the District of Delaware, alleging Novo Nordisk's attempt to outbid Pfizer violates the Clayton Antitrust Act.
  • Novo Nordisk launched a takeover bid on Thursday valuing Metsera at around $6 billion, triggering a four business days renegotiation deadline and following Pfizer's earlier $4.9 billion offer with potential total consideration up to $7.3 billion.
  • Pfizer's new filing broadens allegations to include Metsera's controlling stockholders and names Validae Health, Population Health Partners, and two ARCH Venture funds as co-conspirators under the Clayton Antitrust Act.
  • Metsera said `Pfizer is trying to litigate its way to buying Metsera for a lower price than Novo Nordisk` and will address the claims in court, as the dispute escalates.
  • Pfizer lacks a marketed weight-loss product and targeted Metsera for two late-stage candidates, whose GLP-1 agonist and amylin analogue offer once-monthly dosing versus weekly rivals, with analysts estimating $5 billion peak sales.
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Business Wire broke the news in Crystal River, United States on Sunday, November 2, 2025.
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