Pathway activation model for personalized prediction of drug synergy

Postdoctoral Researcher Personalised Medicine _ University of Groningen - Academic Hive

The Groningen Research Institute of Pharmacy (GRIP) is looking for Postdoctoral Researcher on Personalised Medicine _ University of Groningen.

Pathway activation model for personalized prediction of drug synergy

Targeted monotherapies for cancer often fail due to inherent or acquired drug resistance. By aiming at multiple targets simultaneously, drug combinations can produce synergistic interactions that increase drug effectiveness and reduce resistance. Computational models based on the integration of omics data have been used to identify synergistic combinations, but predicting drug synergy remains a challenge. Here, we introduce Drug synergy Interact…