US EditionParity and lactation induce T cell mediated breast cancer protection
- New Nature-published research shows that, according to Professor Loi, pregnancy and breastfeeding leave behind long-lived immune cells in breast tissue that may reduce the risk of triple-negative breast cancer.
- More than 300 years ago, researchers studying nuns linked childlessness to higher breast cancer rates; prior studies estimated a 7 per cent risk reduction per birth and 4.3 per cent per 12 months breastfeeding.
- In lab tests, analysing tissue from 260 women aged 20–70 revealed mothers had more long-lived T cells in healthy breast tissue, while mouse experiments showed full lactation led to smaller tumours and removing T cells erased protection.
- Professor Sherene Loi said the findings could enable new prevention and treatment approaches, including vaccines and immune treatments to replicate breastfeeding's protection and reduce breast cancer incidence.
- Public-Health data show although 96 per cent of Australian mothers initiate breastfeeding, only 16 per cent exclusively breastfeed at six months, and women giving birth later and breastfeeding less may raise breast cancer risk.
14 Articles
14 Articles
Breastfeeding can build immunity against breast cancer, study shows
Australian researchers have found breastfeeding can protect women against breast cancer by building up their immunity. According to a new study, pregnancy and breastfeeding produces infection-fighting T-cells that help guard against abnormal cells that could develop into cancer.
Aussie researchers discover breakthrough link between breastfeeding and fighting cancer
Australian scientists have made a breakthrough discovery in why breastfeeding and pregnancy reduces the long-term risk of breast cancer in women.It is widely accepted that childbirth and breastfeeding can protect women against the deadly disease – but until now, the biological reason has been linked to hormones.Researchers at the Peter MacCallum Cancer Centre in Victoria, led by Professor Sherene Loi, have found that childbirth develops infect…
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