Study Reveals Acidic Conditions as Key to Pancreatic Cancer Survival

Study reveals acidic conditions as key to pancreatic cancer survival

Tumors are not a comfortable place to live: oxygen deficiency, nutrient scarcity, and the accumulation of sometimes harmful metabolic products constantly stress cancer cells.

Acidic tumor environment promotes survival and growth of pancreatic cancer cells, study shows

Tumors are not a comfortable place to live: oxygen deficiency, nutrient scarcity, and the accumulation of sometimes harmful metabolic products constantly stress cancer cells.

Pancreatic Cancer Cells Rely on Acidic Environment to Survive

A new study published today in Science has shown for the first time how an acidic pH in the tissue surrounding pancreatic cancer cells triggers changes in their mitochondria that contribute to faster tumor growth, metastasis, and treatment resistance.  As a solid tumor develops, its environment can increasingly become more acidic in a process known as acidosis. While previous studies had drawn a link between acidosis and tumor aggressiveness in …