Nasal Epithelial Assays Predict Cystic Fibrosis Clinical Outcomes

Owlstone Medical announces investment of up to $2.3 million USD from the Cystic Fibrosis Foundation to develop a breath test for Pseudomonas aeruginosa detection in cystic fibrosis patients

Owlstone Medical ("Owlstone"), the global leader in Breath Biopsy® for applications in early disease detection and precision medicine, today announced that the Cystic Fibrosis Foundation has made an up to USD $2.3 million equity investment (circa £1.7 million) in Owlstone to develop a breath test for Pseudomonas aeruginosa (PA) detection in patients with cystic fibrosis (CF).

Nasal Epithelial Assays Predict Cystic Fibrosis Clinical Outcomes

A new study supports the clinical utility of human nasal epithelial cultures as predictive biomarkers for cystic fibrosis CFTR modulator therapy.

Levels of vitamins D, A increase with Kaftrio, study finds

Children and adolescents with cystic fibrosis (CF) treated with Kaftrio, marketed as Trikafta in the U.S., experienced increases in the fat-soluble vitamins D and A for up to one year, according to a study from Spain. Treatment reduced the proportion of participants with vitamin D and vitamin A deficiency, the study found. But the vitamin A increase seen at six months in participants treated with Orkambi (ivacaftor/lumacaftor) or Symkevi (tezaca…