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Top Cystic Fibrosis News Today News

Pharmacists warn drug shortage affecting cancer patients

NHS · United Kingdom

Pharmacists warn drug shortage affecting cancer patients

Coverage: 7 sources

NBD1 stabilizers safe in healthy volunteers, Sionna says

Mississippi · Mississippi

NBD1 stabilizers safe in healthy volunteers, Sionna says

SION-719 and SION-451, NBD1 stabilizers from Sionna, will advance in development after positive safety results in Phase 1 trials.Read Article

I’m still waiting for spring to bring me back to life

Pennsylvania · Pennsylvania

I’m still waiting for spring to bring me back to life

We’ve been having such a slow-developing spring here in Pennsylvania. The temperatures have been lower than normal, and it feels like it’s been raining for months. I must continually remind myself not to complain about it. Yet some years, it’s felt like we’ve gone from freezing cold and snow to extreme heat overnight, which left us begging for a slow spring warmup. I guess there’s always something to complain about if you’re looking for it. So m…Read Article

Inhaled antibiotics linked to increased risk of fungal infections

Using inhaled antibiotics may increase the risk of fungal infections with Aspergillus fumigatus in cystic fibrosis patients, per a study.Canada · Canada Read Article

‘It’s not contagious’: How to address stigmas about the CF cough

This piece is part of a series about living with invisible illness for Cystic Fibrosis Awareness Month. Read more here. While cystic fibrosis (CF) is an invisible illness, it can be heard. That trademark gurgling, wet, productive CF cough sets many on edge because the cause remains invisible. My cough has produced numerous awkward situations. A person yelled at me on an airplane because he couldn’t sleep thanks to my cough, and a concerned nurse…Read Article

Signaling molecule PI5P may treat M. abscessus CF lung infections

Scientists have discovered a potential therapy for cystic fibrosis (CF) patients who are infected with Mycobacterium abscessus, a bacterium that can cause serious lung infections. They found that a signaling molecule called PI5P can boost the antimicrobial activity of immune cells isolated from patients against the bacterium. This happens even for cells from patients not eligible for treatment with Kaftrio, a CFTR modulator therapy that’s market…Italy · Italy Read Article

Breathing space: Advocating for CF needs without overexplaining

This is part of a series about living with invisible illness for Cystic Fibrosis Awareness Month. Go here to read more. People don’t need to explain themselves when they need to take a lunch break to eat or sleep after a long day. That would be exhausting. How much more exhausting would it be to have an energy-devouring disease, yet still feel the pressure to explain yourself every time you care for your needs, like asking for extra rest, accomm…Read Article

MRSA infections linked to worse outcomes for children in CF study

In young children with cystic fibrosis (CF), infections with methicillin-resistant Staphylococcus aureus (MRSA) are linked to more antibiotic use, worse lung function, and more lung damage by early school age, according to a study led by researchers in Brazil. Because infections with MRSA appear to indicate more severe disease and can be serious and difficult to treat, doctors should design a clear and standardized plan to eliminate these bacter…Brazil · Brazil Read Article

In this awareness month, a look inside a largely invisible disease

Columnist Jennifer Bleecher takes readers on a tour of the complications caused by the invisible disease of cystic fibrosis.Read Article

ATS 2025: ETI-Linked Mucus Clearance Tied to Lung Function Gains in Paediatric CF - Pharmaceutical Technology

Data presented at ATS 2025 showed that lung improvement in paediatric cystic fibrosis (CF) patients receiving ETI therapy is driven by regional mucus plug clearance.Mississippi · Mississippi See the Story

Ivacaftor essential component of CF treatment Trikafta: Study

Ivacaftor, a component of the triple-combination therapy Trikafta, is essential to restore mucus clearance in people with cystic fibrosis (CF), a study reports. The study was launched after previous work using CF airway cells suggested that long-term exposure to ivacaftor limited the restoration of CFTR, the protein that’s faulty or absent in CF patients. However, researchers demonstrated that different cell culture conditions profoundly affecte…Germany · Germany Read Article

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