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One of the world's oldest blood pressure drugs may also halt aggressive brain tumor growth

Hydralazine blocks the oxygen-sensing enzyme ADO, inducing senescence in glioblastoma cells and halting tumor growth, researchers report after testing human brain tumor cells.

Summary by Medical Xpress
A Penn-led team has revealed how hydralazine, one of the world's oldest blood pressure drugs and a mainstay treatment for preeclampsia, works at the molecular level. In doing so, they made a surprising discovery—it can also halt the growth of aggressive brain tumors.

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Medical Xpress broke the news in on Sunday, November 16, 2025.
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