One in four people with mood disorders show internal circadian misalignment

One in four people with mood disorders show internal circadian misalignment

Young people with emerging mood disorders often show signs of internal circadian misalignment—a disruption in the timing between key biological rhythms—and those with greater misalignment tend to report more severe depressive symptoms. That’s according to new research published in the Journal of Biological Rhythms, which used lab-based physiological measurements to examine how circadian signals like melatonin, cortisol, and core body temperature…