Eating Olive Oil Before Carbs Has a Surprising Effect on Blood Sugar
The effect persisted in mice with type 2 diabetes and was linked to faster gut hormone release and slower stomach emptying.
- Kyoto University researchers found that consuming olive oil before glucose reduces blood sugar spikes in mice, offering a potential dietary strategy for managing glucose levels.
- Scientists investigated meal-sequencing, a strategy of eating fat or protein before carbohydrates, to understand how nutrient timing influences hormone secretion and gastric emptying. Prior clinical studies suggested this approach could moderate post-meal glucose rises.
- Consuming fat 15 minutes before glucose increased early secretion of GLP-1, GIP, and glucagon while slowing gastric emptying. These beneficial effects persisted even in mice with type 2 diabetes and severe insulin deficiency.
- "Meal-Sequencing is appealing because it merely changes how a meal is eaten," said Daisuke Yabe, corresponding author at Kyoto University, noting the approach avoids restricting specific food groups.
- Future clinical studies are necessary to determine whether the coordinated hormone-nerve response observed in mice can improve blood sugar regulation in humans with and without diabetes.
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24 Articles
Scientists Had Mice Eat Olive Oil Before Carbs, And It Changed Their Blood Sugar Response
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Ingesting fat before carbohydrates can dampen the initial increase in glucose after eating.
Eating olive oil before carbs has a surprising effect on blood sugar
A simple change in the order you eat your food could help prevent blood sugar spikes. Scientists discovered that giving mice olive oil before carbohydrates slowed digestion and activated a surprising combination of hormones and nerve signals that helped regulate blood sugar, even in mice with type 2 diabetes.
A new study shows that the order of food intake significantly affects blood sugar levels after eating.
Consuming fat before carbohydrates reduces post-meal blood glucose
In treating diabetes, post-meal elevation of glucose levels is an important therapeutic target. Existing clinical studies indicate that eating vegetables, protein, or fat before carbohydrates can moderate a post-meal rise in blood glucose, pointing to the potential of meal-sequencing as a simple and sustainable dietary strategy.
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