US EditionSugar-Coated 'Sticky' Stem Cells Could Unlock Surgery-Free Liver Treatments
UNIVERSITY OF BIRMINGHAM, JUL 10 – Coating hepatic progenitor cells with natural sugars increases liver tissue adhesion and engraftment, addressing up to 90% cell failure in current therapies, researchers said.
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Cell Coating Method Could Overcome Major Hurdle for Liver Cell Therapy
Researchers at the University of Birmingham and the Swiss company InSphero have developed a new method to improve the engraftment of cells into the liver by coating them with hyaluronic acid molecules. Their findings, published in Communications Biology, show promise to improve the efficacy of regenerative cell therapies for a wide range of liver diseases without relying on genetic modification. “Liver transplants are the only option for many s…
The addition of bile acids as farnesoid X receptor agonists to the culture medium promoted the growth and development of unique stem cell-derived liver organoids, researchers from Japan report. These three-dimensional liver organoids were able to develop sustainably and long-term...
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