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No. 22 Iowa State takes on Colorado in Big 12 play

Both teams face extensive injury lists with 12 players out for each and several others doubtful or questionable, posing challenges for Saturday's Big 12 matchup, officials said.

  • On Oct. 11, Iowa State visits Colorado at Folsom Field with BetMGM College Football Odds opening Iowa State by 3.
  • Combining both teams' reports shows an unprecedented total of THIRTY EIGHT players sidelined, with Colorado Buffaloes listing 12 out and Iowa State Cyclones listing 12 out, one doubtful and four questionable.
  • Iowa State will be without key defensive backs, including Jontez Williams and Jeremiah Cooper for the season, while Hykeem Williams, DeKalon Taylor and Simeon Price are also out; coach Matt Campbell said kicker Kyle Konrardy is unavailable for the Colorado game.
  • Colorado's recent 35-21 loss to TCU adds urgency to lineup decisions as Iowa State ranks 118th in red zone offense scoring on 75% of trips, while Colorado's defense ranks 54th at 81.8%.
  • The Big 12 will update injury reports Thursday and Friday nights, and Deion Sanders hopes to get a few players back this week.
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Associated Press News broke the news in United States on Wednesday, October 8, 2025.
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