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Nicholas Brendon, a star of ‘Buffy the Vampire Slayer,’ is dead at 54

Nicholas Brendon, known for Buffy the Vampire Slayer, died in his sleep at 54; family highlighted his recent passion for painting and ongoing health struggles.

  • Actor Nicholas Brendon, best known for playing Xander Harris on 'Buffy the Vampire Slayer,' died Friday, March 20, at age 54 in his sleep of natural causes, his family confirmed.
  • Brendon faced significant health challenges in later years, including cauda equina syndrome requiring multiple spinal surgeries and a congenital heart defect discovered after a 2023 cardiac incident.
  • Identical twin brother Kelly Donovan noted Brendon found creative passion in painting recently; his family described his artwork as 'one of the purest reflections' of his personality while he remained optimistic about his future.
  • Co-Star Alyson Hannigan posted an Instagram tribute calling Brendon her 'Sweet Nicky,' thanking him for 'years of laughter, love and Dodgers.' Fans mourned the actor who helped redefine the nerd archetype in American culture.
  • Brendon is the second 'Buffy' cast member to die in recent years, following actress Michelle Trachtenberg's 2025 passing. His journey reflects the complex experiences of performers managing long-term health challenges and public visibility.
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On Friday, March 20, Nicholas Brendon’s death was confirmed at age 54; the actor was recognized for his work in series as “Buffy the Vampires” and “Criminal Minds.” Nicholas Brendon was admired for his role as Xander Harris in “Buffy the Vampires” and for his work in films such as “Demond Island” and “Unholy”. What did Nicholas Brendon die of? this revealed his familyThe family of Nicholas Brendon shared a statement on social networks, where the…

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UPI broke the news in Washington, United States on Friday, March 20, 2026.
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