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NHS England to develop ‘world-first’ database for genes linked to cancer

NHS England's new register of 120 cancer-linked genes aims to enable earlier screening and personalized treatment, benefiting tens of thousands of patients, officials said.

  • NHS England is building the NHS National Inherited Cancer Predisposition Register to catalogue 120 genes linked to cancer, described as the first of its kind by Professor Peter Johnson.
  • Following the Lynch syndrome register, NHS England created the new register so family members of cancer patients and people who have cancer can compare genes for earlier screening and personalised treatments.
  • Those identified with inherited risk will be added to the register and automatically invited to screening and routine tests, while patients could be tested for treatment responsiveness to guide NHS clinicians.
  • The database could expedite access to earlier screening and testing and personalised treatment for thousands of patients and enable tens of thousands to check inherited cancer risk.
  • Campaigners welcomed the register as transformative, while officials said it forms part of NHS efforts to modernise care and support the forthcoming National Cancer Plan for England with joined-up access for researchers and clinical teams.
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13 Articles

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The database containing 120 at-risk gene types can give not only patients but also their family members a chance for survival and prevention

·Budapest, Hungary
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Evening StandardEvening Standard
+5 Reposted by 5 other sources
Center

NHS England to develop ‘world-first’ database for genes linked to cancer

The health service is developing a register of 120 genes known to increase the likelihood of getting cancer as part of a 10-year plan.

·London, United Kingdom
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Lean Right

Genetic tests for cancer on the NHS

·London, United Kingdom
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The Telegraph broke the news in London, United Kingdom on Friday, January 23, 2026.
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