New study shows LSD changes brain connectivity in unique ways compared to MDMA and amphetamines

New study shows LSD changes brain connectivity in unique ways compared to MDMA and amphetamines

A new brain imaging study has revealed that lysergic acid diethylamide (LSD) alters brain connectivity in ways that are notably different from methylenedioxyamphetamine (MDMA) and d-amphetamine. While all three substances disrupt communication within certain brain networks, LSD produces broader and more distinctive changes—especially in regions associated with self-awareness and sensory processing. The findings suggest that not all substances of…