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Study Reveals Interhemispheric Brain Circuit Crucial for Spatial Memory

Optogenetic blocking of the circuit impaired location memory and navigation, while a 22q11.2 deletion mouse model showed weaker interhemispheric connections.

Summary by News Medical
A team led by the Institute for Neurosciences (IN), a joint center of the Spanish National Research Council (CSIC) and Miguel Hernández University of Elche (UMH), has identified a brain circuit essential for spatial memory.

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The two hemispheres of the hippocampus are connected by a brain circuit to coordinate spatial memory, according to a study conducted in mice and led by the Institute of Neurosciences (IN), a mixed center of the Higher Council of Scientific Research (CSIC) and the Miguel Hernández de Elche University (UMH).

A team from the Institute of Neurosciences, a mixed center of the Miguel Hernández de Elche University and the Higher Council for Scientific Research (CSIC), has identified an essential brain circuit for spatial memory, a finding that not only helps to understand how the brain remembers locations and is oriented in space, but also provides a new clue about cognitive deficits associated with psychiatric disorders such as schizophrenia. The work, …

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Medical Xpress broke the news in on Tuesday, April 14, 2026.
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