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New Published Case Series Explores Umbilical Cord Tissue Allografts in Plantar Fascia Care

Nine patients with plantar fasciopathy showed a 61% pain reduction and 50% functional improvement after a single Wharton's jelly allograft, with no adverse reactions reported.

  • Following peer-reviewed publication in Biomedicines, Regenative Labs announced a study published Sept. 24, 2025, reporting 90-day improvements in plantar fasciopathy outcomes.
  • Described by the authors as a degenerative collagen-based condition, plantar fasciopathy involved patients who failed at least three months of conservative therapy and used Wharton's jelly, umbilical cord-derived connective tissue rich in extracellular matrix.
  • The study used a single ultrasound-guided 2 cc injection of 150 mg/mL Wharton's jelly, under IRB oversight, following FDA- and AATB-aligned tissue processing protocols, in nine patients.
  • Reported outcomes showed a 60.98% mean improvement in NPRS at Day 90, with no adverse reactions reported, according to the study.
  • Given study limitations, authors disclosed relationships with Regenative Labs, including company involvement, and noted small sample size and absence of control group, calling for larger prospective trials.
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New Published Case Series Explores Umbilical Cord Tissue Allografts in Plantar Fascia Care

PENSACOLA, Fla., Feb. 4, 2026 /PRNewswire/ -- Regenative Labs, in collaboration with Babak Baravarian, DPM, Director of Foot & Ankle Research at University Foot & Ankle Institute, today announced the publication of a new observational case series examining the use…

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PR Newswire broke the news in United States on Thursday, February 5, 2026.
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