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New Oral Antiretroviral Shows Potential as Long-Acting HIV Pre-Exposure Prophylaxis

MK-8527, a novel nucleoside reverse transcriptase translocation inhibitor, offers a promising once-monthly oral HIV prevention method, potentially improving adherence and privacy.

Summary by News Medical
A new HIV antiretroviral shows promise as a long-acting, oral prophylactic agent, according to a new study by Izzat Raheem, Tracy Diamond and colleagues from Merck & Co., Inc., Rahway, NJ, USA, published August 26th in the open-access journal PLOS Biology.

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Medical Xpress broke the news in on Tuesday, August 26, 2025.
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