Rare loss-of-function variants in HECTD2 and AKAP11 confer a risk of bipolar disorder - PressReach

Understanding Mental Health in the Workplace: How Employers Can Support Employees with Bipolar Disorder

Photo by cottonbro studio Mental health in the workplace is a growing concern, especially as more people begin to discuss their struggles with mental health conditions openly. One of the most misunderstood and challenging conditions that employees may face is bipolar disorder. This mental health disorder, characterized by extreme mood swings, can significantly affect an individual’s ability to perform in the workplace. Employers, however, can pl…

Spring Forward, Fall Back - International Bipolar Foundation

As daylight savings time (DST) has arrived, the time shift plays a significant role for those of us who live with bipolar disorder (BD). For me, a solid and consistent routine, combined with positive lifestyle management, has contributed to my euthymic (stable) state. Even a minor change to my sleep cycle can trigger a mood disturbance, leading to symptoms of an episode. Bipolar disorder thrives on inconsistency. While the one-hour change may se…

Rare loss-of-function variants in HECTD2 and AKAP11 confer a risk of bipolar disorder

Scientists at deCODE genetics, a subsidiary of Amgen, reveal today in Nature Genetics associations between rare loss-of-function variants in two genes and bipolar disorder. REYKJAVIK, Iceland, March 25, 2025 /PRNewswire/ — Bipolar disorder is characterized by extreme mood swings, bouts of mania or hypomania, and episodes of depression.  It is a highly heritable and serious condition, that […]

Rare loss-of-function variants in HECTD2 and AKAP11 confer a risk of bipolar disorder - PressReach

Scientists at deCODE genetics, a subsidiary of Amgen, reveal today in Nature Genetics associations between rare loss-of-function variants in two genes and bipolar disorder. REYKJAVIK, Iceland, March 25, 2025 /PRNewswire/ — Bipolar disorder is characterized by extreme mood swings, bouts of mania or hypomania, and episodes of depression.  It is a highly heritable and serious condition, that when untreated comes with a high suicide rate.  While the…

New Genetic Risk Factors for Bipolar Disorder Revealed

Research led by deCODE genetics in Iceland has revealed genetic variants in two genes, AKAP11 and HECTD2, convey a previously unknown risk for bipolar disorder. Although this is the first time either of these genes has been linked with bipolar disorder, variants in AKAP11 have been linked to psychosis and schizophrenia in the past. “Bipolar disorder is a serious psychiatric condition and has a large impact on individuals and society; if untreate…