Neanderthals May Have Been Running a Sophisticated 'Fat Factory' in Germany 125,000 Years Ago
Summary by Smithsonian Mag
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Neandertal variant reduces activity of a key muscle enzyme
11.07.2025 - New study shows that a genetic variant inherited from Neandertals impairs the function of a key enzyme involved in muscle performance. To the point. Reduced enzyme activity: The Neandertal variant in AMPD1 decreases its enzymatic activity by 25 percent in laboratory-produced proteins and by up to 80 percent in the muscles of genetically engineered mice.
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