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Merck in Talks to Buy Biotech Revolution in up to $32 Billion Deal, FT Reports

Merck aims to strengthen its oncology pipeline with Revolution Medicines’ RAS inhibitor drugs, addressing upcoming patent expirations on key cancer treatments.

  • Thursday, Merck & Co. reportedly entered talks to acquire Revolution Medicines Inc. in a $28–$32 billion deal, but neither company immediately commented and talks could be weeks away.
  • With Keytruda's protection ending in 2028, Merck & Co. has been acquiring assets like $9.2 billion and $10 billion targets, and earlier this year Revolution raised $2 billion via Royalty Pharma, people familiar with the matter say.
  • Market reaction was swift: chatter first reported by the Financial Times sparked a 16% pre-market jump lifting Revolution's valuation above $24 billion, then shares rose 15.14% overnight to $123.65, while AbbVie Inc. was linked to talks on Thursday before denying involvement.
  • If the deal closes, it would be the largest biotech transaction since Pfizer Inc.'s $43 billion Seagen acquisition and secure Revolution's daraxonrasib pipeline for PDAC and NSCLC.
  • Near term, Revolution's clinical calendar shows RMC-5127, a RAS G12V-selective inhibitor, is due to start human testing later this quarter and data in previously treated PDAC are expected this year.
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Reuters broke the news in United Kingdom on Thursday, January 8, 2026.
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