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Merck Exercised the Option for the Global Rights of Abbisko Therapeutics's Pimicotinib

  • On April 1, 2025, Beijing Time, Abbisko Therapeutics announced that Merck has exercised its option for global commercialization rights to pimicotinib .
  • In December 2023, Abbisko Therapeutics and Merck entered into an exclusive licensing agreement, referred to as "the Agreement", concerning pimicotinib, a CSF-1R inhibitor.
  • Pimicotinib demonstrated positive topline results in the Global Phase III MANEUVER Study for tenosynovial giant cell tumor with an objective response rate of 54.0% at Week 25 compared to 3.2% for placebo , and was generally well-tolerated.
  • The option exercise fee is USD85.0 million, adding to the USD70.0 million upfront payment Abbisko received in February 2024, with potential for up to USD605.5 million in total payments plus double-digit royalties.
  • Merck's decision to exercise the option deepens its collaboration with Abbisko, reflecting a shared commitment to advancing new treatment options in rare oncology and delivering a potentially best-in-class therapy to patients with TGCT, who currently have limited treatment options.
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Merck Exercised the Option for the Global Rights of Abbisko Therapeutics's Pimicotinib

SHANGHAI, March 31, 2025 /PRNewswire/ -- On April 1, 2025, Beijing Time, Abbisko Therapeutics Co., Ltd. ("Abbisko Therapeutics") announced that Merck has exercised the global commercialization option for pimicotinib (ABSK021), with an option exercise fee of USD85.0 million, under the…

·Altavista, United States
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The Bradford Era broke the news in Bradford, United States on Tuesday, April 1, 2025.
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