Exposure to Air Pollution in Womb Increases Risk of Asthma
- Researchers presented a 2025 mouse study in San Francisco showing that prenatal air pollution exposure increases adult offspring asthma risk.
- The study builds on prior research linking maternal pollution exposure to childhood asthma and explores epigenetic mechanisms affecting lung and immune genes.
- Pregnant mice exposed to pollution produced adult offspring with stronger allergen-triggered airway constriction and altered DNA methylation in thousands of lung genes.
- Dr. Razia Zakarya noted an epigenetic "memory effect" persisting into adulthood, with tested pollution levels meeting WHO air quality guidelines.
- The findings highlight the need to shield expectant mothers from exposure to air pollutants and underscore the importance of further investigation into the molecular mechanisms involved, as well as potential methods to reverse epigenetic modifications.
33 Articles
33 Articles


Exposure to air pollution in womb increases risk of asthma: study
Scientists also found that the children of mothers exposed to pollutants during pregnancy had lasting changes affecting their lungs.

Exposure to air pollution in womb increases risk of asthma
Scientists also found that the children of mothers exposed to pollutants during pregnancy had lasting changes affecting their lungs.
Maternal air pollution exposure worsens asthma severity for offspring
A mother's exposure to air pollution during pregnancy can increase asthma risk in her adult offspring, according to a new mouse study published at the ATS 2025 International Conference. Researchers also found that offspring had lasting epigenetic changes affecting their lungs and immune response.
Your bad asthma might be due to your mother’s exposure to air pollution
New research has found a link between exposure to air pollution during pregnancy and an increased risk of the offspring developing asthma as an adult. The study looked at how a mother being exposed to air pollution – before and during pregnancy, and while breast feeding – can increase the risk of asthma in her children, even if those children are never directly exposed to the pollution themselves. Researchers, from the School of Life Sciences at…
New research links asthma risk to combined impact of urban environments
A landmark European study has found that people living in built-up areas with limited green space, high levels of pollution, and exposure to artificial light at night face a significantly higher risk of developing asthma. The findings come from EXPANSE, a major EU-funded project that analysed data from 14 population cohorts across Europe. Researchers studied over 349,000 individuals and identified around 7,400 new asthma cases. What sets this st…
Maternal Air Pollution Exposure Worsens Asthma Severity for Offspring
A mother’s exposure to air pollution during pregnancy can increase asthma risk in her adult offspring, according to a new mouse study published at the ATS 2025 International Conference. Researchers also found that offspring had lasting epigenetic changes affecting their lungs and immune response.
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