US EditionChristina Applegate hospitalized amid kidney infection: ‘Pain that I’ve never felt before’
LOS ANGELES, AUG 7 – Christina Applegate was hospitalized with a severe kidney infection spreading to both kidneys, requiring intravenous antibiotics amid her ongoing battle with multiple sclerosis, diagnosed in 2021.
- Recording from her Los Angeles hospital, Applegate revealed on August 5, 2025, she was hospitalized seven days for a severe kidney infection during a live MeSsy podcast.
- After feeling unwell in Europe, Applegate insisted on being admitted to the hospital upon returning to the United States.
- Amid excruciating pain, Applegate screamed before an emergency CT scan at 2 a.m. revealed a kidney infection that spread to her left kidney.
- Following hospital care, Applegate received intravenous antibiotics and is now recuperating at home.
- Amid her MS journey, Applegate revealed she’s been hospitalized more than 30 times earlier this year and announced her You With The Sad Eyes memoir due March 3, 2026.
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57 Articles
Actress Christina Applegate is facing new health challenges. The star, who has multiple sclerosis, revealed in a new episode of her podcast, recorded from the hospital, that she has kidney inflammation that has spread to both kidneys, and the pain was so severe that she was screaming.
Christina Applegate hospitalized amid kidney infection: 'Pain that I've never felt before'
TAMPA, Fla. (WFLA) – Actress Christina Applegate has revealed that she was recently hospitalized with an infection that spread to both kidneys. The "Married… with Children" and "Dead to Me" star, who is battling multiple sclerosis, shared the news in the Aug. 5 episode of her "MeSsy" podcast, which she recorded from a hospital in Los Angeles. Applegate told co-host Jamie-Lynn Sigler ("The Sopranos") that she began to feel something was wrong dur…
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