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Making Inroads into the Regulation of Reprogramming Induced Rejuvenation
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Making Inroads into the Regulation of Reprogramming Induced Rejuvenation
Reprogramming involves exposing cells to expression of one or more of the Yamanaka factors, c-Myc, Oct4, Sox2, and KLF4. This slowly alters cell state in a small fraction of exposed somatic cells, and these cells transform to become induced pluripotent stem cells, essentially the same as embryonic stem cells. This recapitulates some of the processes involved in embryogenesis. More rapidly and reliably than this change of state, a cell exposed to…
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