Passage Bio Reports Progress in Gene Therapy for Frontotemporal Dementia
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2 Articles
Passage Bio Reports Progress in Gene Therapy for Frontotemporal Dementia
PHILADELPHIA, PA — Passage Bio, Inc. (NASDAQ: PASG) has announced encouraging updates from the ongoing Phase 1/2 upliFT-D clinical trial for PBFT02, a one-time gene therapy for frontotemporal dementia (FTD) caused by granulin (GRN) mutations. The data reflect robust biomarker improvements and durable effects, supporting the promise of PBFT02 as a groundbreaking treatment for this devastating neurodegenerative disease. PBFT02, using a gene replac…
An interdisciplinary team—leaded by Dr. Isabel Lastres-Becker, of the Instituto de Investigaciones Biomédicas “Sols-Morreale” and the Department of Biochemistry of the Autonomous University of Madrid (UAM)—has investigated the... La entrada Madrid researchers achieve neuroprotective effects in a model of frontotemporal dementia was first published in Gazetín Madrid.
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