This Gene Is Linked to Lower Alzheimer's Risk – And We May Finally Know Why
3 Articles
3 Articles
This Gene Is Linked to Lower Alzheimer's Risk – And We May Finally Know Why
There's something special about the APOE2 variant of the APOE (apolipoprotein E) gene: People who carry it tend to live longer, and they have a lower risk of developing Alzheimer's disease. Scientists are still trying to figure out why, and now, they have a new lead. A team led by researchers at the Buck Institute for Research on Aging in the US set out to answer that question using human stem cell-derived neurons and mouse studies. "We've known…
'Longevity gene' may protect the brain from Alzheimer's by boosting DNA repair, study finds
A longevity gene called APOE2 helps brain cells repair DNA damage and resist aging, potentially explaining why carriers have lower Alzheimer's risk, a new study suggests.
Researchers at the Buck Institute for Research on Aging in the United States have identified the protective mechanism associated with the APOE2 gene, which is linked to a lower risk of developing Alzheimer's disease. The study, published in the journal Aging Cell, reveals how this variant of the APOE (apolipoprotein E) gene contributes to longevity and brain health. The study reveals the protective mechanism of the APOE2 gene. The research demon…
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