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Long-Term Melatonin Might Harm Heart Health, Study Says

  • Recently, Researchers from the American Heart Association reported that prolonged melatonin supplement use of at least 12 months is associated with higher risks of heart failure, hospital admission, or death.
  • AHA researchers analysed five years of medical records comparing adults with chronic insomnia documented melatonin users to non-users, excluding those on other sleep drugs or with prior heart failure.
  • The analysis showed melatonin users had a 90 per cent greater likelihood of heart failure, were 3.5 times more likely to need hospitalisation, and saw mortality rates rise from 4.3 percent to 7.8 percent.
  • The study team urged further research to confirm melatonin's cardiovascular safety, while Essentia Health officials said the research is early and medical researchers noted inability to prove causation.
  • In the US melatonin is sold over the counter while in the United Kingdom it is prescription-only, and limited long-term evidence prompts calls for prospective trials amid health records differences.
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A preliminary analysis suggests that prolonged melatonin use may be associated with a higher risk of heart failure and death.

·Budapest, Hungary
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Easton Spectator broke the news in on Friday, October 31, 2025.
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