Keto Diet and Depression: New Research Shows Potential Benefits for More Difficult-to-Treat Depression

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A more detailed analysis showed that those participants who had the most severe symptoms of depression at the start of the study benefited the most.

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Oxford – A ketogenic diet with less than 30 g of carbohydrates per day may offer some benefit for treatment-resistant depression. This is suggested by a randomized controlled trial from Great Britain, the results of which have now been published in JAMA Psychiatry (2026; DOI: 10.1001/jamapsychiatry.2025.4431). The study...