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Ivonescimab Plus Chemo Shows Stronger NSCLC Response Than Tislelizumab Combo

  • Akeso announced positive Phase III results for ivonescimab plus chemotherapy on April 22, 2025.
  • The HARMONi-6 study compared this combination to tislelizumab plus chemotherapy for first-line squamous lung cancer.
  • This trial enrolled 532 patients across 66 centers in China.
  • Interim data showed improved progression-free survival outcomes and a similar safety profile.
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Ivonescimab in Combination with Chemotherapy Demonstrates Statistically Significant and Strongly Positive Results in First-Line Treatment of Squamous Non-Small Cell Lung Cancer (sq-NSCLC) vs. Tislelizumab in Combination with Chemotherapy

HONG KONG, April 22, 2025 /PRNewswire/ -- Akeso, Inc. (9926.HK) ("Akeso" or the "Company") is both pleased and honored to announce that its global first-in-class PD-1/VEGF bispecific antibody, ivonescimab, in combination with chemotherapy, has demonstrated strongly positive results in the…

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Charleston Gazette-Mail broke the news in Charleston, United States on Wednesday, April 23, 2025.
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