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Investigation of baicalin, baicalein and low-dose sulfasalazine for orocecal transit time determination in saliva and plasma

Abstract The application of high-dose sulfasalazine (≥ 500  mg) followed by plasma or salivary sampling represents an established method for orocecal transit time determination. In the present study, we aimed to establish an alternative procedure. For this, we investigated. whether the onset of baicalin or its aglycon baicalein in plasma or saliva after oral application correlated with the onset of sulfapyridine in plasma and. whether the onse…
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Pharma Excipients broke the news on Saturday, April 18, 2026.
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