New Single-Protein Analysis Technique Provides Unprecedented Information on Scramblases

New single-protein analysis technique provides unprecedented information on scramblases

A new single-protein analysis technique gives researchers an unprecedented ability to study proteins called scramblases, which have critical roles in biology.

Scramblase Dynamics Uncovered by Single-Vesicle Fluorescence Microscopy

A new single-protein analysis technique gives researchers newfound ability to study scramblases, physiologically important proteins that translocate phospholipids bidirectionally across cell membranes.   In the study published in Nature Structural & Molecular Biology titled, “A single-vesicle fluorescence microscopy platform to quantify phospholipid scrambling,” researchers from Weill Cornell Medicine and Ruhr University Bochum have developed a …

Tracking Individual Membrane Translocation Accelerates Precision Microscopic Drug Screening Efforts

A new single-protein analysis technique gives researchers an unprecedented ability to study proteins called scramblases, which have critical roles in biology.

Innovative Tool Advances Research on Essential Proteins

A groundbreaking advancement in the study of membrane proteins has been unveiled by researchers from Weill Cornell Medicine and Ruhr University Bochum, introducing an innovative fluorescence imaging-based technique that measures the activity rates of individual scramblase proteins. This novel methodology surpasses conventional ensemble approaches by providing an unprecedented, single-molecule resolution into the dynamics of scramblases—integral …