Innovative method enables large-scale analysis of metabolites in biological samples

New method enables comprehensive analysis of metabolites in biological samples

Researchers from the McCullagh Group in Oxford University's Department of Chemistry have published an innovative method in Nature Protocols today (22 August) that provides comprehensive analysis of metabolites found in cells, tissues and biofluids.

Innovative method enables large-scale analysis of metabolites in biological samples

Researchers from the McCullagh Group in Oxford University's Department of Chemistry have published an innovative method in Nature Protocols that provides comprehensive analysis of metabolites found in cells, tissues and biofluids.

Large-Scale Metabolomics Enabled by Anion-Exchange Chromatography Mass Spectrometry

When ion-exchange chromatography and mass spectrometry are coupled using electrochemical ion suppression, it allows for the selective and specific analysis of highly polar and ionic compounds. The method has been particularly useful in advancing the fields of environmental chemistry, food chemistry, forensics, and cell biology. More recently, anion-exchange chromatography mass spectrometry (AEC-MS) has been used in metabolomics. Now, researchers…

Breakthrough Technique Enables Large-Scale Study of Polar and Ionic Metabolites

Researchers from the McCullagh Group in Oxford University's Department of Chemistry have published an innovative method in Nature Protocols today (22 August) that provides comprehensive analysis of metabolites found in cells, tissues and biofluids.

Scientists Unveil Breakthrough Technique for Large-Scale Metabolite

Revolutionizing Metabolomics: A Breakthrough Ion-Exchange Chromatography-Mass Spectrometry Protocol In a landmark development poised to transform the field of metabolomics, researchers from Oxford University’s Department of Chemistry, led by Professor James McCullagh, have unveiled an innovative analytical protocol that markedly advances the large-scale analysis of metabolites in biological samples. This novel technique, described in a study […]