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Study Finds Link Between Inflammation and Fatigue in Cancer Patients
Researchers linked inflammation to physical and general fatigue in 192 women with early-stage breast cancer, with effects lasting up to 18 months post-treatment, study shows.
- Researchers at UCLA analyzed protein markers in 192 women with early-stage breast cancer before radiation or chemotherapy and across 18 months, finding inflammation linked to some cancer-related fatigue.
- Activation of inflammatory responses by the tumor or cancer treatment appears to drive cancer-related fatigue, which causes physical, emotional, and cognitive tiredness, motivating researchers at UCLA.
- Measured proteins revealed surprisingly different associations across fatigue dimensions: TNF-α, sTNF-RII and IL-6 linked to greater general fatigue, physical fatigue correlated with TNF-α, sTNF-RII and CRP, while emotional fatigue showed inverse links to TNF-α and sTNF-RII.
- Researchers suggested cancer care teams explore inflammation management, noting behavioral interventions like physical activity, cognitive behavioral therapy, and mindfulness meditation may ease fatigue in patients with early-stage breast cancer.
- Adjusting for demographics and cancer stage, the links still held as women reported multiple fatigue dimensions and provided blood for protein testing, highlighting the need for targeted treatments.
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32 Articles
32 Articles
The Norfolk Daily News+28 Reposted by 28 other sources
Inflammation Linked To Fatigue Among Cancer Patients
Coverage Details
Total News Sources32
Leaning Left5Leaning Right2Center9Last UpdatedBias Distribution56% Center
Bias Distribution
- 56% of the sources are Center
56% Center
L 31%
C 56%
13%
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