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Hidden Mechanism Driving Joint Tissue Growth in Rheumatoid Arthritis Has Been Found

The findings suggest a new treatment target as the cells also stimulate fibroblasts and rely on IL-6 signaling, researchers said.

Summary by Medical Xpress
Researchers at Hospital for Special Surgery (HSS) have identified a specialized population of immune cells that plays a central role in driving abnormal tissue growth in rheumatoid arthritis (RA), offering new insight into disease progression and potential treatment strategies. The study, published in Science Translational Medicine, reveals that a subset of immune cells known as SPP1ʰⁱ macrophages works in tandem with structural cells and protei…

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HSS Researchers Identify Hidden Mechanism Driving Joint Tissue Growth in Rheumatoid Arthritis

NEW YORK--(BUSINESS WIRE)--Jun 25, 2026-

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Medical Xpress broke the news on Wednesday, June 24, 2026.
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