TCT 2025: Deferring Treatment of Non-Culprit Lesions “Remains an Option” for STEMI in Multivessel Disease

Immediate Complete iFR-guided Revascularization is Not Superior to Deferred Revascularization of Non-Culprit Lesions Guided by Cardiac MRI in STEMI Patients with Multivessel Disease

Three-year findings from the iMODERN trial show that instantaneous wave-free ratio (iFR)-guided revascularization performed during the initial procedure is not superior to deferred cardiac magnetic resonance (CMR)-guided management of non-culprit lesions for patients with ST-segment elevation myocardial infarction (STEMI) and multivessel disease.

TCT 2025: Deferring treatment of non-culprit lesions “remains an option” for STEMI in multivessel disease

Robin Nijveldt New data suggest that interventionalists can safely opt to defer the treatment of non-culprit lesions when addressing ST-segment elevation myocardial infarction (STEMI) and multivessel coronary artery disease. This is the finding at three years of a trial of two revascularisation strategies for STEMI in patients with multivessel disease, in which instantaneous wave-free ratio (iFR)-guided revascularisation was shown not to be supe…