Causes Of Pancreatitis: Dr. Indrannel Saha Explains Risk Factors And Preventive Measures by Dr. Indraneel Saha

El Pais

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Pancreatic cancer usually builds a kind of wall around it. A dense and fibrous layer, full of cells and substances at its service, that helps it isolate itself and hide from the immune system to continue growing without stopping. Thus it survives. This microenvironment, called stroma, represents, in fact, most of the tumor and is responsible, among other factors, for the extreme aggressiveness of this disease: survival at the age of five of a di…

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One study highlights the role of fibroblasts in the progression of pancreatic cancer. Read more Research reveals keys to the aggressiveness of pancreatic cancer in News.es.

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Now, a team of researchers from the Research Institute of the Hospital del Mar, the IIBB-CSIC-IDIBAPS, the Mayo Clinic, the Institute of Biology and Experimental Medicine (CONICET, Argentina) and the CaixaResearch Institute has identified a new determining factor that affects this characteristic of pancreatic cancer: a function of Galectin-1 protein within the nucleus of fibroblasts. This discovery, published in the journal PNAS, provides new ke…

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The study opens the door to new therapeutic strategies for one of the cancers with the highest mortality rates

CRCT - Centre de Recherches en Cancérologie de Toulouse

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Identification of fibroblasts associated with pancreatic cancer with anti-tumor activity Pancreatic cancer, Pancreatic star cells, Fibroblasts associated with cancer, endoplasmic reticulum, Collagen, Extracellular matrix, BiP.