8 Articles
8 Articles
Heterotopic Porcine Cardiac Xenotransplantation in the Intra-Abdominal Position in a Non-Human Primate Model
Heterotopic cardiac transplantation in the intra-abdominal position in a large animal model has been essential in the progression of the field of cardiac transplantation. Our group has over 10 years of experience in cardiac xenotransplantation with pig to baboon models, the longest xenograft of which survived over 900 days, with rejection only after reducing immunosuppression. This article aims to clarify our approach to this model in order to a…
Human immune response to pig kidney transplants mapped, identifying early rejection markers
A pioneering study has provided unprecedented insights into the immune response following pig-to-human kidney xenotransplantation. The findings, presented today at the ESOT Congress 2025, mark a significant step forward in overcoming the biggest challenge in xenotransplantation: rejection by the human immune system.
Insight into distribution and composition of nonhuman N-Glycans in mammalian organs via MALDI-TOF and MALDI-MSI
The major hurdle of xenotransplantation is the immune response triggered by human natural antibodies interacting with carbohydrate antigens on the tra…
Study finds how pig kidney transplants work in humans, spots...
Last Updated on June 30, 2025 by Team THIP New Delhi, June 30 (IANS) With xenotransplantation — animal-to-human transplantation — poised to address the global organ shortage crisis, a pioneering study has outlined how human immune cells interact with pig kidney tissue in transplanted organs, revealing critical early markers of rejection and potential intervention strategies. […] The post Study finds how pig kidney transplants work in humans, spo…
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