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Human brain is two separate organs, research finds
- On Friday, Stanford-led researchers published findings in Nature Neuroscience revealing the human brain develops from two distinct neural systems rather than a single progenitor cell, challenging decades of scientific consensus.
- Genetic analysis shows progenitor cells expressing the gene Otx2 form the forebrain and midbrain, while cells expressing Gbx2 follow a separate developmental path to create the hindbrain.
- This two-part blueprint extends back over 500 million years, appearing in diverse species including zebrafish and acorn worms, which share a distant common ancestor with humans.
- Scientists successfully grew hindbrain motor neurons in a lab for the first time, providing a new model to study spinal muscular atrophy and amyotrophic lateral sclerosis .
- Developmental biologist Rayyan Jokhai noted the research could accelerate investigations into brainstem conditions, ultimately aiding development of regenerative therapies for patients with these genetic disorders.
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41 Articles
New discovery overturns a prevailing model of brain development
For centuries, scientists have thought of the brain as a single, unified organ. But new research led by Stanford Medicine reveals that what we call the brain is two distinct organs that evolved independently over hundreds of millions of years.
·Mona Vale, Australia
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"We showed for the first time that the frontal part of the brain originates in a parent cell completely different from the back," said one of the authors of the study published this Friday.
·Lisboa, Portugal
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The IndependentReposted by 
The Independent (US)
The Independent (US)Human brain is actually two separate organs, scientists find
The Stanford University breakthrough stands to open new doors for research into fatal neurodegenerative diseases
·London, United Kingdom
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The consequence may be important for studying diseases such as spinal muscle atrophy and amyotrophic lateral sclerosis. Both affect motor neurons.
·Madrid, Spain
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Total News Sources41
Leaning Left4Leaning Right7Center9Last UpdatedBias Distribution45% Center
Bias Distribution
- 45% of the sources are Center
45% Center
L 20%
C 45%
R 35%
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