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How SSRIs affect serotonin receptors: New findings from a depression study

Summary by PsyPost

A study of depressed individuals found that an eight‐week treatment with selective serotonin reuptake inhibitors (SSRIs) reduced the activity of 5-HT4 receptors—a specific type of serotonin receptor—in the neostriatum region of the brain. This finding is consistent with the expectation that the treatment increases the concentration of the neurotransmitter serotonin in the brain. The paper was published in Biological Psychiatry. Depression, or ma…

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How SSRIs affect serotonin receptors: New findings from a depression study

A study of depressed individuals found that an eight‐week treatment with selective serotonin reuptake inhibitors (SSRIs) reduced the activity of 5-HT4 receptors—a specific type of serotonin receptor—in the neostriatum region of the brain. This finding is consistent with the expectation that the treatment increases the concentration of the neurotransmitter serotonin in the brain. The paper was published in Biological Psychiatry. Depression, or ma…

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PsyPost broke the news in 2 days ago on Thursday, February 20, 2025.

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