UFC 322: Della Maddalena Vs. Makhachev Full Fight Card Betting Odds
Islam Makhachev aims to become a two-division UFC champion by moving up to welterweight to challenge Jack Della Maddalena, who defends his title at UFC 322.
- On Saturday, November 15, 2025, Madison Square Garden hosts UFC 322, where reigning UFC welterweight champion Jack Della Maddalena defends his title against former UFC lightweight champion Islam Makhachev, who moves up to 170 pounds.
- Islam Makhachev is moving up because he seeks to cement a legacy as a two-division champion after a dominant lightweight run, while Jack Della Maddalena defends his welterweight crown earned earlier this year.
- Also on the card, Bet365 lists Makhachev as a 275 favorite with Della Maddalena at +225, while Valentina Shevchenko is favored 125 against Zhang Weili.
- A win for Makhachev would create a two-division UFC champion and reshape several title pictures, with key questions on how he handles welterweight size and Della Maddalena's striking.
- Coverage will continue as fight night nears, with the main card on ESPN+ pay-per-view and prelims on ESPN+ and ESPN2.
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14 Articles
UFC 322 odds, predictions and betting preview: Makhachev vs. Della Maddalena headlines at MSG
UFC 322 takes over Madison Square Garden in New York City on Saturday, November 15, 2025, with one of the most anticipated title fights of the year. Reigning welterweight champion Jack Della Maddalena defends his belt against former lightweight king Islam Makhachev, who moves up to 170 pounds in pursuit of a second world title. Makhachev enters unbeaten in the UFC since 2015 and aims to cement his legacy as a two-division champion. Della Maddale…
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