Early-Onset Gastrointestinal Cancer Rates Rising Across the Globe
UNITED STATES, JUL 7 – Early-onset colorectal cancer incidence in U.S. adults under 50 rose from 5.9 to 8.4 cases per 100,000 between 2000 and 2017, linked to obesity and lifestyle factors.
- On July 8, 2025, Oxford University Press published a paper led by Sara Char showing early-onset gastrointestinal cancer rates rising globally.
- The rise results from unclear causes, though experts blame modern lifestyle factors and most cases occur sporadically, according to authors from Dana Farber.
- Studies report significant increases among young adults in Europe and the US, including a 185% rise in 20–24-year-olds and doubling of risk with obesity in women.
- Sara Char noted that there is a global increase in gastrointestinal cancers among individuals under 50 years old, with delayed diagnoses common and aggressive treatments often applied despite limited benefits in survival.
- These findings imply urgent need for research on biology, better screening, and tailored care to address growing cases and unique challenges for younger patients.
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11 Articles


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The incidence of early-stage gastrointestinal cancer is increasing dramatically worldwide, especially among young people, according to a large-scale analysis detailing the state of the disease worldwide.
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