Does Tofacitinib Worsen Postoperative Complications in Acute Severe Ulcerative Colitis?

Does Tofacitinib Worsen Postoperative Complications in Acute Severe Ulcerative Colitis?

A head-to-head comparison with infliximab offers reassurance regarding concerns of tofacitinib potential worsening of postoperative complications.

Good News for Tofacitinib in Recent Study of Acute Severe UC

A head-to-head comparison of the JAK inhibitor drug tofacitinib and chimeric monoclonal antibody infliximab in the treatment of acute severe ulcerative colitis (ASUC) shows that, contrary to concerns, tofacitinib is not associated with worse postoperative complications and in fact may reduce the risk of the need for colectomy. “Tofacitinib has shown efficacy in managing ASUC, […] The post Good News for Tofacitinib in Recent Study of Acute Severe…