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Published • United States • Updated

Genetic Protection from Type 1 Diabetes Resulting from Accelerated Insulin mRNA Decay

Summary by Stemwell Science News
Investigators discovered that the inositol-requiring enzyme 1α (IRE1α) digestion motif was present in insulin mRNA carrying SNP rs3842752. This SNP in the 3′ untranslated region of insulin gene associated with protection from T1D. [Cell] Full ArticlePress ReleaseGraphical Abstract
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Stemwell Science NewsStemwell Science News

Genetic Protection from Type 1 Diabetes Resulting from Accelerated Insulin mRNA Decay

Investigators discovered that the inositol-requiring enzyme 1α (IRE1α) digestion motif was present in insulin mRNA carrying SNP rs3842752. This SNP in the 3′ untranslated region of insulin gene associated with protection from T1D. [Cell] Full ArticlePress ReleaseGraphical Abstract

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Wharton Journal-SpectatorWharton Journal-Spectator
+2 Reposted by 2 other sources

Genprex Collaborators Selected to Present Positive Preclinical Data on Diabetes Gene Therapy at the 2025 American Diabetes Association 85th Scientific Sessions

Novel Gene Therapy Program is Addressing Type 1 and Type 2 Diabetes

·Wharton, United States
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Wharton Journal-Spectator broke the news in Wharton, United States on Tuesday, March 25, 2025.
Sources are mostly out of United States (3)

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