Gene editing restores hearing and balance in adult mice with DFNA41 deafness

Gene editing restores hearing and balance in adult mice with DFNA41 deafness

Zheng-Yi Chen, DPhil, associate scientist at the Eaton-Peabody Laboratories, and Ines and Fredrick Yeatts Chair in Otolaryngology, at Mass Eye and Ear, is the senior and co-corresponding author of a paper published in the Journal of Clinical Investigation, "Single Dose Genome Editing Therapy Rescues Auditory and Vestibular Functions in Adult Mice with DFNA41 Deafness."

Laying the foundation for gene editing for inherited progressive deafness in adults

A study, published in the Journal of Clinical Investigation titled "Single Dose Genome Editing Therapy Rescues Auditory and Vestibular Functions in Adult Mice with DFNA41 Deafness," provides an example of a successful use of gene-editing technology to treat a mouse model of human genetic hearing loss.