Gabapentinoids associated with severe exacerbation of COPD

Gabapentinoids associated with severe exacerbation of COPD

A population-based cohort study of more than 10,000 persons using gabapentinoids found that their use was associated with an increased risk of chronic obstructive pulmonary disease (COPD) exacerbation. This study supports the warnings from regulatory agencies and highlights the importance of considering this potential risk when prescribing gabapentin and pregabalin to patients with COPD. The study is published in Annals of Internal Medicine.