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First patient dosed in study of Corbus’ next-generation CB1 Inverse Agonist CRB-913 for the treatment of obesity

Summary by bariatricnews.net
The first patient has been dosed in Corbus Pharmaceuticals in the single ascending dose/multiple ascending dose (SAD/MAD) portion of the Phase 1 trial of CRB-913 for the treatment of obesity. The study is being conducted in the US under an open IND.CRB-913 is a second-generation, highly peripherally restricted cannabinoid type-1 (CB1) receptor inverse agonist drug designed to treat obesity. CB1 inverse agonism is a clinically validated mechanism…
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First patient dosed in study of Corbus’ next-generation CB1 Inverse Agonist CRB-913 for the treatment of obesity

The first patient has been dosed in Corbus Pharmaceuticals in the single ascending dose/multiple ascending dose (SAD/MAD) portion of the Phase 1 trial of CRB-913 for the treatment of obesity. The study is being conducted in the US under an open IND.CRB-913 is a second-generation, highly peripherally restricted cannabinoid type-1 (CB1) receptor inverse agonist drug designed to treat obesity. CB1 inverse agonism is a clinically validated mechanism…

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bariatricnews.net broke the news in on Monday, March 31, 2025.
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