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FDA to consider warning against antidepressants

UNITED STATES, JUL 21 – FDA experts debated stronger warnings on SSRIs in pregnancy amid concerns over fetal risks and untreated maternal depression affecting 1 in 5 pregnant women, panelists said.

  • On Monday, an FDA panel convened to discuss the risks and benefits of using selective serotonin reuptake inhibitors during pregnancy.
  • The panel was convened amid concerns about SSRI exposure affecting fetal development, though studies showed unclear links to long-term child outcomes.
  • Experts debated that untreated maternal depression raises risks like suicide and low birth weight, so SSRIs remain vital with shared decision-making.
  • Dr. Adam Urato stated, "SSRIs cross the placenta, affecting fetal brain development," and called for stronger warning labels on these medications.
  • No consensus emerged from the meeting, but the panel suggested the FDA may consider revising SSRI label warnings while balancing treatment benefits and risks.
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contemporaryobgyn.net broke the news in on Monday, July 21, 2025.
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