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FDA Approves First Non-Opioid Painkiller in Over Two Decades

  • The U.S. Food and Drug Administration approved Vertex Pharmaceuticals' Journavx, the first non-opioid painkiller in over 20 years, for short-term pain following surgery or injuries.
  • Journavx provides more relief than a dummy pill but does not outperform a common opioid-acetaminophen combination pill, according to studies.
  • Vertex's drug works by blocking proteins that trigger pain signals, differing from opioids that bind to brain receptors.
  • Experts see promise in Journavx's unique mechanism, though its effectiveness and lengthy development process highlight challenges in pain management.
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